The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

On Friday, the San Francisco 49ers shared the news that tight end George Kittle may not play on Sunday against the Los ...

The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

George Kittle is doubtful for Sunday's game at Los Angeles with a hamstring injury, while two of San Francisco's top ...

After an upset loss to the Minnesota Vikings in Week 2, the three 49ers most to blame are Jake Brendel, Brandon Aiyuk, and ...

Problematic quarterback contracts are exacerbating the NFL’s typical early-season fear and dread. There are a number of ...

Coming off a Super Bowl victory as the Patriots ' de facto defensive coordinator, Flores went to the Dolphins as their next ...

After the Panthers dispatched Darnold, the 49ers signed him to be Brock Purdy’s backup. In Coach Kyle Shanahan’s system, he ...

SportsLine's model simulated Los Angeles Rams vs. San Francisco 49ers 10,000 times and made its Week 3 NFL picks, predictions ...

The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

Fortunately, the 49ers have landed the ideal Week 3 foe to help make things right in the Los Angeles Rams, who are somehow ...

No surprise at all to see C.J. Stroud and the Houston Texans start the season with two consecutive wins. Big surprise to see ...